Sodium Valproate

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Sodium Valproate Specification

Ph Level
7.5-8.5

Loss on Drying
Not more than 1.0%

Solubility
Freely soluble in water and alcohol

Heavy Metal (%)
Less than 10 ppm

Molecular Weight
166.19 g/mol

Color
White

Boiling point
Not applicable (decomposes before boiling)

Particle Size
Micronized

Poisonous
Non-poisonous at therapeutic doses toxic in high doses

Molecular Formula
C8H15NaO2

EINECS No
214-844-0

Structural Formula
CH3-CH2-CH2-CH(C2H5)-COONa

Shelf Life
2 years

Storage
Store in a cool dry place and away from light

HS Code
29159070

Taste
Slightly salty

Smell
Odorless

Melting Point
120-125C

Medicine Name
Sodium Valproate

Chemical Name
Sodium 2-propylpentanoate

CAS No
1069-66-5

Type
Pharmaceutical Compound

Grade
Pharmaceutical Grade

Usage
Treatment of epilepsy migraines and bipolar disorder

Purity(%)
99%

Appearance
White crystalline powder

Physical Form
Solid

About Sodium Valproate

Valproate (VPA), also known valproic acid, sodium valproate, and divalproex sodium, is a medication primarily used to treatepilepsy and bipolar disorder and to prevent migraine headaches.

Valproate (VPA), are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches. It is useful for the prevention of seizures in those with absence seizures, partial seizures, and generalized seizures. It can be given intravenously or by mouth. Longacting formulations exist.

Specifications:

CAS NO: 99-66-1
Chemical Formula : C8H16O2
MOL. WEIGHT: 144.211g/mol

Pharmaceutical Grade and Purity

Sodium Valproate is produced with superior standards, ensuring a pharmaceutical grade with a purity of 99%. Rigorous quality control limits heavy metal content to less than 10 ppm, and the product undergoes strict tests for loss on drying, maintaining less than 1.0%. Each batch is micronized for optimal absorption and bioavailability.

Applications and Benefits

Renowned for its efficacy, Sodium Valproate is used as a first-line agent in managing epilepsy, controlling migraines, and stabilizing mood swings in bipolar disorder. Its rapid solubility and bioavailability allow it to act efficiently, providing sustained control of symptoms, improving patient quality of life and daily functioning.

Safe Storage and Handling

To preserve potency and shelf life, Sodium Valproate should be stored in a cool, dry environment away from light. The white, odorless, crystalline powder is stable under recommended conditions and should be kept tightly sealed to avoid contamination and degradation. Always follow storage and handling instructions for safety and maximum efficacy.

FAQs of Sodium Valproate:

Q: How is Sodium Valproate used in the treatment of epilepsy, migraines, and bipolar disorder?

A: Sodium Valproate works by stabilizing electrical activity in the brain, which helps control seizures in epilepsy, reduce the frequency of migraines, and manage mood fluctuations in bipolar disorder. It is usually administered orally under medical supervision with dosing adjusted according to individual needs.

Q: What is the recommended storage condition for Sodium Valproate?

A: Sodium Valproate should be stored in a cool, dry location away from direct light. Proper storage helps maintain its effectiveness and extends its shelf life to up to 2 years. Make sure the container is sealed tightly to prevent moisture or contamination.

Q: When should Sodium Valproate be administered for best results?

A: Sodium Valproate is typically taken at the same time each day, as prescribed by a healthcare professional. Consistency in administration helps maintain steady drug levels in the body, optimizing therapeutic outcomes for epilepsy, migraine, or bipolar disorder.

Q: Where does the manufacturing and export of Sodium Valproate take place?

A: Sodium Valproate is manufactured and exported by recognized pharmaceutical companies in India, meeting stringent quality and safety standards for global supply as a raw pharmaceutical material.

Q: What benefits does Sodium Valproate offer compared to other treatments?

A: Sodium Valproate offers broad-spectrum activity with proven effectiveness in seizure control, migraine prevention, and mood stabilization. Its high purity and pharmaceutical grade ensure optimal absorption and consistent therapeutic effects, improving patient compliance and quality of life.

Q: How should Sodium Valproate be handled to ensure safety?

A: Handle Sodium Valproate in its solid, white crystalline form using gloves and in a well-ventilated area. Avoid inhaling dust and ensure all surfaces and containers remain clean and dry to maintain product integrity. Dispose of any unused material according to local regulations.

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