About Pantoprazole with Domperidone Capsules
Pantoprazole with Domperidone Capsules
The combination of domperidone and pantoprazole is marketed by Rewine Pharmaceuticals.
Pharmacokinetics
Pantoprazole acts by selectively inhibiting the H+/K+-ATPase enzyme in the secretory canaliculus of the stimulated parietal cell. Domperidone stimulates GI activity by acting as a competitive antagonist at dopamine D2-receptors.
Pantoprazole + Domperidone Adverse Reactions / Pantoprazole + Domperidone Side Effects
Pantoprazole: Diarrhoea, dizziness, pruritus, skin rashes, GIT infections; anaphylaxis, angioedema, chest pain, dyspnoea, erythema multiforme, gastroenteritis, hyperglycaemia, infection, Inj site reaction, jaundice, optic neuropathy, anterior ischaemia, pancreatitis, speech disorder. Domperidone: Headache, insomnia, nervousness, dizziness, thirst, lethargy, irritability, GI disturbances, hot flushes, mastalgia, galactorrhoea, gynaecomastia, menstrual irregularities, rash, pruritus, urticaria, stomatitis, conjunctivitis, urinary frequency, dysuria, oedema, palpitations, leg cramps, asthaenia, drug intolerance.
Special Precautions
Lactation. Pantoprazole: Not recommended in child <12 years. Long-term therapy may lead to bacterial overgrowth in the GIT. Domperidone: Increases serum prolactin levels resulting to galactorrhoea in females and gynaecomastia in males. Hypertensive crisis in patients with phaeochromocytoma.
Other Drug Interactions
Care should be exercised when domperidone is administered in combination with MAO inhibitors.
Dosage
Oral
Gastro-oesophageal reflux disease, Dyspepsia
Adult: Per tablet/capsule contains pantoprazole 40 mg and domperidone 10 mg: 1 tablet/capsule once daily.
Dual-Action Relief for Digestive DiscomfortPantoprazole with Domperidone Capsules offer a synergistic approach to gastrointestinal issues. Pantoprazole reduces acid production in the stomach, while Domperidone promotes healthy movement of food through the digestive tract. This combination addresses both the symptoms and underlying causes of acidity and ulcers for comprehensive relief.
Easy Administration and StorageThese capsules are designed for convenient oral administration. Patients are advised to take the medication as directed by their healthcare provider. For optimal effectiveness and longevity, the capsules should be kept in a dry place, away from moisture and direct sunlight.
Assured Quality from Trusted ManufacturersProduced in India by experienced exporters, manufacturers, and suppliers, these capsules meet stringent quality benchmarks. The product supports global demand for reliable, general pharmaceutical solutions and is backed by robust manufacturing processes.
FAQs of Pantoprazole with Domperidone Capsules:
Q: How do Pantoprazole with Domperidone Capsules help in treating acidity and heartburn?
A: Pantoprazole reduces gastric acid production, while Domperidone enhances gastrointestinal motility. Together, they provide dual relief from symptoms like acidity, heartburn, and stomach ulcers.
Q: What is the recommended way to take these capsules?
A: These capsules should be taken orally with water, preferably before meals, as advised by a healthcare provider for maximum effectiveness.
Q: When is the best time to use Pantoprazole with Domperidone Capsules?
A: It is generally recommended to take the capsules before meals, once daily or as directed by your physician, to manage and prevent acidity and discomfort.
Q: Where should I store these capsules for best results?
A: Pantoprazole with Domperidone Capsules should be stored in a dry place, away from heat and moisture, to preserve their potency and shelf-life.
Q: What are the main benefits of using this combination formulation?
A: This combination provides rapid relief from acid-related discomfort, helps heal stomach ulcers, and improves digestive function with a single, convenient capsule.
Q: How are these capsules manufactured and supplied from India?
A: Produced by reputed Indian exporters, manufacturers, and suppliers, the capsules undergo strict quality checks before global distribution to ensure safety and efficacy.
Q: What is the process for obtaining these capsules from an Indian supplier?
A: Interested buyers can contact certified exporters, manufacturers, or suppliers in India to place bulk orders, ensuring compliance with regulatory and quality requirements.