Diltiazem Hydrochloride

Get a Price/Quote

Diltiazem Hydrochloride Specification

Structural Formula
C6H2ClNO4C6H17NO3S

Molecular Weight
451.98 g/mol

Shelf Life
2 years when properly stored

Loss on Drying
Less than 0.5%

Poisonous
NO

Ph Level
5.5 - 6.5 (10% aqueous solution)

Heavy Metal (%)
Less than 10 ppm

Storage
Store in a cool dry place away from moisture and light

Particle Size
Less than 10 microns

Smell
Odorless

Taste
Bitter

Solubility
Freely soluble in water and methanol

EINECS No
251-403-2

Color
White to off-white

Molecular Formula
C22H27ClN2O4S

HS Code
29349900

Boiling point
Decomposes before boiling

Melting Point
208-210C

Medicine Name
Diltiazem Hydrochloride

Chemical Name
Diltiazem Hydrochloride

CAS No
33286-22-5

Type
Pharmaceutical Active Ingredient

Grade
USP/EP/BP Grade

Usage
Used in the treatment of hypertension angina and certain arrhythmias

Purity(%)
99.0%

Appearance
White to off-white crystalline powder

Physical Form
Solid

About Diltiazem Hydrochloride

Diltiazem hydrochloride

Diltiazem is a potent vasodilator. The drug is indicated for anginal.

Diltiazem hydrochloride is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.Diltiazem Hydrochloride is a benzothiazepine calcium channel blocking agent. Diltiazem hydrochloride inhibits the transmembrane influx of extracellular calcium ions into select myocardial and vascular smooth muscle cells, causing dilatation of coronary and systemic arteries and decreasing myocardial contractility. Because of its vasodilatory activity, this agent has been shown to improve the microcirculation in some tumors, thereby potentially improving the delivery of antineoplastic agents to tumor cells.

Potent Solution for Cardiovascular Conditions

Diltiazem Hydrochloride is widely recognized for its effectiveness in treating high blood pressure, angina, and certain types of arrhythmia. Its reliable profile as a calcium channel blocker ensures consistent therapeutic benefits when included in pharmaceutical applications. Manufactured under strict quality controls, it provides dependable outcomes in patient care.

Stringent Quality and Purity Standards

Our Diltiazem Hydrochloride boasts a purity percentage of 99.0%, conforming to USP/EP/BP grades. Benefitting from a refined particle size (less than 10 microns) and minimal impurities (less than 10 ppm heavy metals, under 0.5% moisture loss), it ensures safety and consistency for pharmaceutical manufacturers and healthcare providers alike.

Optimal Storage and Stability

This product remains stable for up to 2 years when stored in a cool, dry place, shielded from moisture and light. Its crystalline solid form is easy to handle and integrate into production processes. The well-defined melting point and pH characteristics enable seamless inclusion into various medicinal formulations.

FAQs of Diltiazem Hydrochloride:

Q: How is Diltiazem Hydrochloride commonly used in medical treatments?

A: Diltiazem Hydrochloride is primarily utilized in the treatment of hypertension, angina, and certain arrhythmias. It acts as a calcium channel blocker, helping to relax blood vessels and improve blood flow, thus reducing blood pressure and heart strain.

Q: What process is followed to manufacture and ensure the purity of Diltiazem Hydrochloride?

A: The manufacturing process adheres to strict pharmaceutical standards, yielding a product with 99.0% purity. The powder is carefully processed to achieve a particle size of less than 10 microns, and quality tests are conducted for heavy metals and moisture content to ensure safety.

Q: When should Diltiazem Hydrochloride be used in pharmaceutical applications?

A: It should be used when formulating medications for treating high blood pressure, managing chronic angina, or addressing specific cardiac arrhythmias, as prescribed by healthcare professionals. It is incorporated into solid dosage forms such as tablets and capsules.

Q: Where should Diltiazem Hydrochloride be stored to maintain its shelf life?

A: It must be kept in a cool, dry environment away from moisture and light. Proper storage ensures the product remains effective and stable up to its marked shelf life of two years.

Q: What benefit does the highly refined particle size provide in formulations?

A: A particle size of less than 10 microns ensures swift and uniform dissolution, enhancing bioavailability and consistent therapeutic effect when used in oral dosage forms.

Q: How do the solubility properties of Diltiazem Hydrochloride facilitate pharmaceutical use?

A: Its excellent solubility in water and methanol enables efficient incorporation during the formulation of solutions and suspensions, contributing to accurate dosing and predictable medicinal effects.

Q: What makes Diltiazem Hydrochloride a preferred choice for global pharmaceutical exporters and manufacturers?

A: Consistent purity, conformity to international grades (USP/EP/BP), reliable supply from India, and rigorous quality controls make it a trusted choice for pharmaceutical exporters, manufacturers, and suppliers worldwide.

Tell us about your requirement