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CINNARAZINE

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CINNARAZINE Specification

Taste
Slightly bitter

Melting Point
119-122C

Storage
Store in a cool, dry place

Molecular Weight
368.51 g/mol

Structural Formula
(C6H5CH=CHCO)N(C6H5) (Not pictured, refer to standard chemistry resources for structure)

HS Code
2933.99.80

Molecular Formula
C26H28N2

Heavy Metal (%)
0.001%

EINECS No
206-066-5

Boiling point
526.3C at 760 mmHg

Shelf Life
24 months

Color
White

Poisonous
Non-poisonous under standard handling

Loss on Drying
0.5%

Solubility
Practically insoluble in water; soluble in alcohol and in acetone

Particle Size
Fine powder

Smell
Odorless

Medicine Name
Cinnarazine

Chemical Name
Cinnarizine

CAS No
298-57-7

Type
Pharmaceutical Raw Material

Grade
Medicine Grade

Usage
Used as an antihistamine and for vertigo

Purity(%)
99%

Appearance
White or almost white powder

Physical Form
Powder

Residual Solvents
Complies with ICH guidelines

Assay
>= 99%

Related Substances
NMT 0.5%

Microbial Limit
Complies with pharmacopeial standards

Identification
By IR and HPLC

Packaging
HDPE drums or as required

CINNARAZINE Trade Information

FOB Port
All Indian Port

Payment Terms
Paypal, Western Union, Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Cash in Advance (CID)

Supply Ability
50 Ton Per Month

Delivery Time
7-10 Days

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Main Export Market(s)
South America, Eastern Europe, Middle East, Central America, Africa, Western Europe, Australia, Asia, North America

Certifications
ISO, GMP, WHO, MSDS

About CINNARAZINE

Product Name: CINNARAZINE

Grade: IP/BP/USP

Cinnarizine is predominantly used to treat nausea and vomiting associated with motion sickness, vertigo, Menieres disease, or Cogans syndrome. In fact, it is one of only a select few drugs that has shown a beneficial effect in the chronic treatment of the vertigo and tinnitus, associated with Menieres disease.

Cinnarizine is an antihistamine and calcium channel blocker of the diphenylmethylpiperazine group.It is also known to promote cerebral blood flow, and so is used to treat cerebral apoplexy, post-trauma cerebral symptoms, and cerebral arteriosclerosis. However, it is more commonly prescribed for nausea and vomiting due to motion sickness or other sources such as chemotherapy, vertigo.

Product Specifications

Molecular Formula
C26H28N2
Storage
Keep away from moisture

Shelf Life
5 Years
Molecular Weight
368.514 g/mol

Chemical Name
CINNARAZINE
CAS No
C26H28N2

Type
Other
Grade
Medicine Grade

Usage
Used to treat nausea and vomiting
Appearance
Off-White to Light Yellow ...

Physical Form
Powder

Premium Quality Assurance

Our Cinnarizine is manufactured and exported from India with a minimum assay of 99%, ensuring exceptional quality and purity. Each batch undergoes rigorous IR and HPLC identification, complies with ICH guidelines for residual solvents, and meets pharmacopeial standards for microbial content and related substances. This commitment delivers a reliable pharmaceutical raw material for consistent formulation outcomes.

Versatile Pharmaceutical Applications

Cinnarizine is primarily used in the formulation of medicines as an antihistamine and to manage symptoms of vertigo. Its high purity and controlled physical properties make it ideal for use in diverse pharmaceutical products. Supplied as a fine powder, it offers excellent solubility in alcohol and acetone, enhancing flexibility for medicine manufacturers.

Safe Packaging and Storage

To preserve its quality, Cinnarizine is packaged in durable HDPE drums or tailored packaging as required. It should be stored in a cool, dry environment, protected from moisture and contaminants, to maintain its stability and maximize shelf life up to 24 months. Our packaging meets international standards, ensuring secure handling and transportation.

FAQs of CINNARAZINE:

Q: How is the quality of Cinnarizine assured during manufacturing?

A: The quality of Cinnarizine is maintained through compliance with pharmaceutical regulations, including an assay of 99%, identification by IR and HPLC, and strict adherence to ICH guidelines for residual solvents. Regular testing ensures related substances do not exceed 0.5% and microbial limits meet pharmacopeial standards.

Q: What are the main uses and benefits of Cinnarizine as a raw material?

A: Cinnarizine is primarily formulated into medicines as an antihistamine and to treat vertigo. Its high purity and controlled particle size make it advantageous for consistent dosing and effective therapeutic outcomes in pharmaceutical preparations.

Q: When should Cinnarizine be stored to preserve its stability?

A: Cinnarizine should be stored immediately after receipt in a cool, dry place. Proper storage is essential to prevent moisture uptake and maintain its efficacy throughout its 24-month shelf life.

Q: Where is your Cinnarizine exported from and how is it packaged?

A: Our Cinnarizine is manufactured and exported from India. It is securely packaged in HDPE drums or as per specific customer requirements, ensuring protection during transit and storage.

Q: What process is followed to ensure Cinnarizine meets pharmacopeial standards?

A: Each batch undergoes comprehensive analysis using IR and HPLC for identification, assays for purity, checks for residual solvents and heavy metals, and testing against pharmacopeial microbial limits, guaranteeing compliance with global pharmaceutical standards.

Q: How should Cinnarizine powder be handled and stored for optimal quality?

A: Handle Cinnarizine in a dry, clean environment, and keep it sealed when not in use. Store it in a cool, dry place, away from moisture and direct sunlight, to preserve its physical and chemical integrity.

Q: What are the solubility and physical properties of Cinnarizine?

A: Cinnarizine appears as a white or almost white, fine, odorless powder. It is practically insoluble in water but dissolves readily in alcohol and acetone, making it adaptable to various pharmaceutical formulations.

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