Amlodipine Besylate

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Amlodipine Besylate Specification

Solubility
Slightly soluble in water freely soluble in methanol.

Shelf Life
2 years when stored under recommended conditions

HS Code
29359070

Heavy Metal (%)
0.001%

Color
White to off-white

Poisonous
Non-poisonous under normal handling

Storage
Store in a cool dry place protected from light and moisture.

Smell
Odorless

Particle Size
Typically <20 microns

Loss on Drying
0.5%

Molecular Weight
567.1 g/mol

EINECS No
Not available

Melting Point
205-209C

Structural Formula
CHOS(CHClNO)

Molecular Formula
C20H25ClN2O5.C6H6O3S

Medicine Name
Amlodipine Besylate

Chemical Name
3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-14-dihydropyridine-35-dicarboxylate benzenesulfonate

CAS No
111470-99-6

Type
Active Pharmaceutical Ingredient (API)

Grade
Pharmaceutical Grade

Usage
Used in the treatment of high blood pressure and angina (chest pain).

Purity(%)
98-102%

Appearance
White or almost white powder

Physical Form
Solid

About Amlodipine Besylate

Amlodipine Besylate is a Long-acting Dihydropyridine Calcium Channel Blocker. It is Effective in the Treatment of Angina Pectoris and Hypertension. Amlodipine is Used with or Without Other medications to Treat high Blood Pressure. Lowering high Blood Pressure helps Prevent Strokes, heart Attacks, And kidneyproblems. Amlodipine Belongs to a Class of Drugs Known As calcium channel Blockers. It Works By Relaxing blood vessels So blood cans Flow More Easily. Amlodipine is also Used to Prevent Certain Types Of chest Pain (angina). It May Help to Increase Your Ability To exercise and Decrease the Frequency of Angina Attacks. It Should Not Be Used to Treat Attacks of Chest Pain When They Occur.

Pharmaceutical Application

Amlodipine Besylate serves as a crucial active pharmaceutical ingredient for treating high blood pressure and angina. Its effectiveness helps prevent acute cardiovascular incidents, ensuring better patient outcomes under medical supervision.

Quality Assurance and Specifications

This API meets rigorous pharmaceutical standards, including a high purity range, low loss on drying (0.5%), and minimal heavy metal content (0.001%). Its solid form is characterized by consistent particle size, ensuring formulation precision.

Optimal Storage Conditions

To preserve its stability and efficacy, Amlodipine Besylate should be stored in sealed containers in a cool, dry environment, protected from light and moisture. Proper storage extends its shelf life up to 2 years.

FAQs of Amlodipine Besylate:

Q: How is Amlodipine Besylate used in pharmaceutical formulations?

A: Amlodipine Besylate is incorporated into medications for the treatment of high blood pressure and angina, typically formulated into tablets due to its solid, powder form and controlled particle size.

Q: What are the benefits of using pharmaceutical-grade Amlodipine Besylate?

A: Pharmaceutical-grade Amlodipine Besylate ensures high purity, minimal impurities, and controlled particle size, which contributes to consistent therapeutic performance and patient safety.

Q: When should Amlodipine Besylate be stored or used to ensure maximum efficacy?

A: For optimal efficacy, Amlodipine Besylate should be used within its 2-year shelf life and stored in a cool, dry location protected from light and moisture to maintain its stability.

Q: Where can Amlodipine Besylate be sourced from?

A: Amlodipine Besylate is exported, manufactured, and supplied by leading pharmaceutical companies in India, ensuring reliable product availability for global healthcare markets.

Q: What is the process of ensuring quality for Amlodipine Besylate?

A: Quality assurance involves stringent purity checks (98-102%), loss on drying tests (0.5%), and heavy metal analysis (0.001%), with all batches checked against regulatory pharmaceutical standards.

Q: Is Amlodipine Besylate poisonous or hazardous?

A: Amlodipine Besylate is non-poisonous under normal handling conditions, making it safe for use in pharmaceutical manufacturing environments when proper guidelines are followed.

Q: What solubility characteristics does Amlodipine Besylate have?

A: Amlodipine Besylate is slightly soluble in water but freely soluble in methanol, which supports various formulation approaches during drug development and manufacture.

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